What is Naltrexone?

Naltrexone is a medication used in medication-assisted treatment (MAT) to treat both opioid and alcohol use disorders. This medication can be given in a pill form or as an injectable. The pill form of naltrexone (ReVia, Depade) can be taken at 50 mg once per day. The injectable extended-release form of the drug (Vivitrol) is administered at 380 mg intramuscular once a month.

What does Naltrexone look like?

How is Naltrexone abused?

Naltrexone blocks the euphoric and sedative effects of drugs such as heroin, morphine, and codeine and is reported to reduce opioid cravings. There is no abuse and diversion potential with naltrexone.

How does Naltrexone affect a person?

Naltrexone works in the brain to prevent opiate effects (e.g., feelings of well-being, pain relief). It also decreases the desire to take opiates or drink alcohol.

What are the health effects/risks of using Naltrexone?

Nausea, headache, dizziness, anxiety, tiredness, and trouble sleeping may occur. In a small number of people, mild opiate withdrawal symptoms may occur, including abdominal cramps, restlessness, bone/joint pain, muscle aches, and runny nose.